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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
9.7
Human Site:
S73
Identified Species:
21.33
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
S73
V
R
G
M
D
S
C
S
L
E
I
A
N
W
R
Chimpanzee
Pan troglodytes
XP_510910
679
74714
S73
V
R
G
M
D
S
C
S
L
E
I
A
N
W
R
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
R69
S
L
E
I
A
N
W
R
N
H
Q
E
T
L
K
Dog
Lupus familis
XP_547058
651
71817
T68
N
W
R
N
H
Q
E
T
L
K
Y
Q
F
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
S68
V
R
A
I
D
S
C
S
L
E
V
A
N
W
K
Rat
Rattus norvegicus
Q5I0E8
657
73037
V68
I
D
S
C
S
L
E
V
A
N
W
R
K
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
N67
S
H
S
L
E
I
V
N
W
R
N
Q
L
E
T
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
F69
L
Q
Y
Q
F
D
V
F
H
G
E
E
T
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
F67
N
K
E
Q
R
K
V
F
T
Y
D
A
A
Y
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
P104
M
Q
G
I
E
T
I
P
A
Q
R
G
V
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
L91
C
V
E
L
Q
P
E
L
K
R
L
K
L
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
73.3
0
N.A.
N.A.
N.A.
0
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
20
20
N.A.
93.3
20
N.A.
N.A.
N.A.
20
20
N.A.
20
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
19
0
0
37
10
0
10
% A
% Cys:
10
0
0
10
0
0
28
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
28
10
0
0
0
0
10
0
0
10
10
% D
% Glu:
0
0
28
0
19
0
28
0
0
28
10
19
0
10
0
% E
% Phe:
0
0
0
0
10
0
0
19
0
0
0
0
10
0
0
% F
% Gly:
0
0
28
0
0
0
0
0
0
10
0
10
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
10
0
0
28
0
10
10
0
0
0
19
0
0
10
0
% I
% Lys:
0
10
0
0
0
10
0
0
10
10
0
10
10
0
28
% K
% Leu:
10
10
0
19
0
10
0
10
37
0
10
0
19
10
0
% L
% Met:
10
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
10
0
10
0
10
10
10
10
0
28
0
0
% N
% Pro:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
19
0
19
10
10
0
0
0
10
10
19
0
0
19
% Q
% Arg:
0
28
10
0
10
0
0
10
0
19
10
10
0
10
19
% R
% Ser:
19
0
19
0
10
28
0
28
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
10
10
0
0
0
19
10
10
% T
% Val:
28
10
0
0
0
0
28
10
0
0
10
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
10
0
10
0
10
0
0
28
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
10
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _